Wonderful oversized early 20th century toothbrush trade sign, likely for use in a pharmacy to promote the Wisdom oral care products. The Wisdom company was originally established over 235 years ago as Addis by its founder William Addis, who is globally recognised as the inventor of the modern-day toothbrush. This whimsical visual three-dimensional piece of bygone advertising memorabilia speaks to a time when advertising and promotion were both direct and artful.